Put the activities (tasks)in their natural succesion order by defining their predecessor-succesor relationships (links).

To create links, move the mouse over the predecessor bar in
Gantt Chart until the cursor
appear and drag to the succesor bar or select
the tasks and click the
icon.
The default link type is Finish-to-Start. To change the type, select the
linked tasks and activate the Details
window (click
icon), or double-click the link arrow in the
chart. Now you can also set the link's lag, that means the duration
between the specified dates of the predecessor and succesor. For
Finish-to-Start, lag time is the
delay between the predecessor's Finish, and the successor's Start. A negative lag is equivalent with a
positive lead time.
A constraint to a task can be set by selecting its type and date in the Details tab in Details window.
Important: moving a task bar in the Gantt graph by dragging it with the mouse cursor will set a start-no-earlier-than (SNET) constraint on the task!
Estimate each activity duration and set it in the duration column.
Some tasks could require different calendars from the project one (e.g.: an activity that cannot be interrupted should have a 24-hours calendar, but the others follow a standard 8-hours calendar). Assign calendars to tasks by clicking in the corresponding cell from Calendar column and selecting the right one. If it's necessary, define additional calendars at the Calendar step in the Guide with the New command, or in the Settings menu, Calendar ( see Part II, Chapter 1, Define calendars section).
Resources use task calendar checkbox in the Details tab will force the assigned resources to work following the task working program. By marking this option the resources will work following task calendar instead its own calendar for the current task. This makes possible to bring a resource to work even for its non-working hours (but working hours for task) Consequently, the resource will accumulate overtime hours (that can be paid with a different hourly rate than regular working hours - see Human Table in Part II, Chapter 2, Section 3)
Edit notes to remember important details related to tasks.
Hint: you may personalize Gantt table by adding or deleting columns, including custom ones. Right click on the header and insert new columns or click on the button in the upper-right corner of the table and mark only the columns you need (see more in 3.4 Tables settings section) .